A Method to Mitigate Refractive Index Mismatch Artefacts for Scanning Laser Optical Tomography

Ole Hill

doi:10.51202/9783959009713

Zusammenfassung

SLOT is a volumetric, multi-modal imaging technique. Point-wise illumination with a weakly focused laser beam results in projection images that are reconstructed into tomographic images. The sample is embedded in a refractive index (RI) matched medium, which prevents light refraction at the sample boundary, which would lead to image artifacts. Silicone oil is used as the immersion medium for SLOT. It is toxic, difficult to remove from samples and can interact with the sample in undesirable ways. Using water as an immersion medium would solve these problems. Unfortunately, the refraction between water and the sample leads to artifacts that drastically degrade the quality of the results. This work aims to eliminate the artifacts through a clever post processing of the sinogram by predicting the refraction of each laser beam. The SLOT simulator was programmed for this purpose. It allows the simulation of SLOT measurements with any RI's and the correction of SLOT measurements with an RI mismatch. Simulated and real SLOT measurements are presented and their similarity is evaluated.

Schlagworte

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Bibliographische Angaben

Copyrightjahr: 2024
ISBN-Print: 978-3-95900-971-3
ISBN-Online: 978-3-95900-971-3
Verlag: TEWISS, Garbsen
Reihe: Berichte aus dem LZH
Band: 04/2024
Sprache: Deutsch
Seiten: 108
Produkttyp: Monographie

Inhaltsverzeichnis

KapitelSeiten

Titelei/Inhaltsverzeichnis Kein Zugriff Seiten I - XII
1 Introduction Kein Zugriff Seiten 1 - 2
1. 1. 2.1.1 State of the Art 3D Imaging of Optics Kein Zugriff
  2. 2.1.2 Ray Propagation at Interfaces of Different RI Kein Zugriff
  3. 2.1.3 RI Matching Kein Zugriff
2. 1. 2.2.1 Beam Path Kein Zugriff
  2. 2.2.2 RI Matching in SLOT Kein Zugriff
  3. 2.2.3 Correction of Image Artifacts Caused by RI Gradients in SLOT Kein Zugriff
  4. 2.2.4 Dejitter Kein Zugriff
  5. 2.2.5 Axis Correction Kein Zugriff
3. 2.3 Quantitative Analysis of Similarity Between Two Images Kein Zugriff
3 Motivation Kein Zugriff Seiten 20 - 21
1. 1. 4.1.1 Ray Propagation Simulation Kein Zugriff
  2. 4.1.2 Simulating SLOT Measurements Kein Zugriff
  3. 4.1.3 Correcting SLOT Measurements with RI Mismatch and Unknown Specimen Geometry Kein Zugriff
2. 1. 4.2.1 RI Match Kein Zugriff
  2. 4.2.2 RI Mismatch and Correction Kein Zugriff
  3. 4.2.3 Numerical Analysis of the Correction Method Kein Zugriff
3. 4.3 Real Measurements with RI Mismatch and Correction Kein Zugriff
4. 4.4 Discussion Kein Zugriff
1. 5.1 Method Kein Zugriff
2. 5.2 Development and Programming Kein Zugriff
3. 5.3 Results Kein Zugriff
4. 5.4 Discussion Kein Zugriff
1. 6.1 Approach: Iterative Determination of the RI Kein Zugriff
2. 6.2 Development and Programming Kein Zugriff
3. 6.3 Feasibility Study / Experimental Setup Kein Zugriff
4. 6.4 Results for Different RI Constellations Kein Zugriff
5. 6.5 Discussion Kein Zugriff
7 Comparison of µCT and SLOT for Printed Optics Kein Zugriff Seiten 85 - 87
8 Conclusion and Outlook Kein Zugriff Seiten 88 - 92
Bibliography Kein Zugriff Seiten 93 - 93
Danksagung Kein Zugriff Seiten 93 - 104
Curriculum Vitae Kein Zugriff Seiten 105 - 108