@book{2025:rivoallan:developmen,
title = {Development of a multiphasic material with continuous gradient for tissue engineering of the osteotendinous and myotendinous junctions},
year = {2025},
note = {Tendons link muscle to bone, enabling movement, but heal poorly. To
improve repair, researchers are developing engineered grafts mimicking
bone-tendon-muscle interfaces. Unique structures at entheses and
myotendinous junctions can guide cell differentiation via
topographical and mechanical cues. Honeycomb scaffolds induced
bone-like differentiation, while aligned fibers promoted tendon fate.
A gradient scaffold with three zones (bone, tendon, muscle) supported
initial co-culture, though high-proliferation cell lines affected
outcomes. Future work involves optimizing scaffold design and using
primary or stem cells for full tissue integration.},
edition = {1},
publisher = {TEWISS},
address = {Garbsen},
series = {Berichte aus dem IMP},
volume = {},
author = {Rivoallan, Nicolas}
}